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Wham is suitable for paired-close Illumina libraries with normal insert sizes (~300bp-500bp). Wham integrates mate-pair mapping, break up go through mapping, delicate-clipping, alternate alignment and consensus sequence based proof to forecast SV breakpoints with one-nucleotide precision. Wham generates a put together pileup (catalog of reads cover

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The delicate-clipped sequences that overhang the breakpoint are collapsed into a consensus sequence using a numerous sequence alignment (MSA) provided from the seqAn library [27]. Wham applies 3 filters for the consensus sequences. Breakpoints will not be described in cases wherever consensus sequences are shorter than 10 bp or comprise in excess o